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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS8
All Species:
5.76
Human Site:
S517
Identified Species:
15.83
UniProt:
Q12929
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12929
NP_004438.3
822
91882
S517
A
V
A
F
K
P
T
S
N
R
H
I
D
R
N
Chimpanzee
Pan troglodytes
XP_528750
1001
111581
S705
S
N
I
Y
T
R
G
S
H
L
D
Q
G
E
A
Rhesus Macaque
Macaca mulatta
XP_001091077
1055
116825
S742
A
V
A
F
K
P
T
S
N
R
H
I
D
R
N
Dog
Lupus familis
XP_534881
791
88639
P486
A
V
A
F
K
P
T
P
N
R
H
M
D
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q08509
821
91720
P516
A
M
P
F
K
S
T
P
N
H
Q
V
D
R
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_416405
831
92642
V520
V
A
A
F
K
Q
T
V
S
R
H
V
D
R
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956536
804
88650
E505
V
L
K
D
E
V
V
E
V
L
D
D
R
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392229
880
100126
A494
R
V
V
D
Q
T
R
A
H
S
D
I
S
V
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785396
970
107261
N675
N
G
P
N
G
H
S
N
G
P
I
G
H
S
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.7
76.1
91.1
N.A.
88.9
N.A.
N.A.
N.A.
79.7
N.A.
51.8
N.A.
N.A.
28.8
N.A.
25.5
Protein Similarity:
100
79
77.1
93.4
N.A.
94.8
N.A.
N.A.
N.A.
88.5
N.A.
66.9
N.A.
N.A.
47.2
N.A.
42.3
P-Site Identity:
100
6.6
100
86.6
N.A.
53.3
N.A.
N.A.
N.A.
60
N.A.
0
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
26.6
100
93.3
N.A.
66.6
N.A.
N.A.
N.A.
73.3
N.A.
20
N.A.
N.A.
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
45
12
45
0
0
0
0
12
0
0
0
0
0
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
23
0
0
0
0
0
0
34
12
56
0
12
% D
% Glu:
0
0
0
0
12
0
0
12
0
0
0
0
0
12
0
% E
% Phe:
0
0
0
56
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
0
12
0
12
0
12
0
0
12
12
0
0
% G
% His:
0
0
0
0
0
12
0
0
23
12
45
0
12
0
12
% H
% Ile:
0
0
12
0
0
0
0
0
0
0
12
34
0
0
0
% I
% Lys:
0
0
12
0
56
0
0
0
0
0
0
0
0
12
0
% K
% Leu:
0
12
0
0
0
0
0
0
0
23
0
0
0
0
0
% L
% Met:
0
12
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
12
12
0
12
0
0
0
12
45
0
0
0
0
0
56
% N
% Pro:
0
0
23
0
0
34
0
23
0
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
12
0
0
0
0
12
12
0
0
12
% Q
% Arg:
12
0
0
0
0
12
12
0
0
45
0
0
12
56
0
% R
% Ser:
12
0
0
0
0
12
12
34
12
12
0
0
12
12
0
% S
% Thr:
0
0
0
0
12
12
56
0
0
0
0
0
0
0
0
% T
% Val:
23
45
12
0
0
12
12
12
12
0
0
23
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _